Life Force Manipulation is the ability to control the flow of an animal or a human's life force. With this ability, one can heal or harm another.
- Shawn Farrell possesses this ability.
Shawn was able to use his ability in two ways: a benevolent way and a malevolent way. He ususally used his ability to heal people at a foundation at the 4400 Center, or whenever he felt threatened he used it to suck away life force. Shawn was able to heal a bird with a broken neck unintentionally, but later was able to use it to heal people with cancer and all sorts of diseases.